What Area of the Foot Is Affected by Cuboid Syndrome?

Cuboid syndrome, a lesser-known but impactful foot ailment, develops in the lateral midfoot region. Situated on the outer side of the foot, the cuboid bone plays a pivotal role in maintaining the stability and functionality of the foot's arch. When this small, cube-shaped bone becomes dislocated or irritated, it gives rise to cuboid syndrome. The affected area often encompasses the lateral aspect of the foot, extending from the midfoot toward the outer edge. Symptoms can include pain, swelling, and a decreased range of motion, affecting the smooth coordination of the foot during movement. Precise anatomical alignment is vital for the cuboid and its neighboring bones, and any disruption can lead to discomfort. If you have endured an injury and there is existing pain in the outer area of your foot, it is suggested that you visit a podiatrist who can accurately diagnose and treat cuboid syndrome.

Cuboid syndrome, also known as cuboid subluxation, occurs when the joints and ligaments near the cuboid bone in the foot become torn. If you have cuboid syndrome, consult with Jeffrey Parrett, DPM from Parrett Podiatry. Our doctor will assess your condition and provide you with quality foot and ankle treatment.

Cuboid syndrome is a common cause of lateral foot pain, which is pain on the outside of the foot. The condition may happen suddenly due to an ankle sprain, or it may develop slowly overtime from repetitive tension through the bone and surrounding structures.


The most common causes of cuboid syndrome include:

  • Injury – The most common cause of this ailment is an ankle sprain.
  • Repetitive Strain – Tension placed through the peroneus longus muscle from repetitive activities such as jumping and running may cause excessive traction on the bone causing it to sublux.
  • Altered Foot Biomechanics – Most people suffering from cuboid subluxation have flat feet.


A common symptom of cuboid syndrome is pain along the outside of the foot which can be felt in the ankle and toes. This pain may create walking difficulties and may cause those with the condition to walk with a limp.


Diagnosis of cuboid syndrome is often difficult, and it is often misdiagnosed. X-rays, MRIs and CT scans often fail to properly show the cuboid subluxation. Although there isn’t a specific test used to diagnose cuboid syndrome, your podiatrist will usually check if pain is felt while pressing firmly on the cuboid bone of your foot.


Just as the range of causes varies widely, so do treatments. Some more common treatments are ice therapy, rest, exercise, taping, and orthotics.

If you have any questions, please feel free to contact our office located in Waxahachie, TX . We offer the newest diagnostic and treatment technologies for all your foot care needs.


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